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Textile Research Journal
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Preparation of Polyethylene Oxide/Chitosan Fiber Membranes by Electrospinning and the Evaluation of Biocompatibility

Ching-Wen Lou

Center of General Education/Institute of Biomedical Engineering and Material Science, Central Taiwan University of Science and Technology, Taichung, Taiwan, Republic of China, cwlou{at}ctust.edu.tw

Jia-Horng Lin

Laboratory of Fiber Application and Manufacturing, Institute of Textile Engineering, Feng Chia University, Taichung, Taiwan, Republic of China

Ko-Chung Yen

Laboratory of Fiber Application and Manufacturing, Institute of Textile Engineering, Feng Chia University, Taichung, Taiwan, Republic of China

Chao-Tsang Lu

Institute of Life Sciences, Central Taiwan University of Science and Technology, Taichung, Taiwan, Republic of China

Chia-Yi Lee

Laboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials, Feng Chia University, Taichung, Taiwan, Republic of China

Chitosan is an excellent material for medical use because it is nontoxic, has good biocompatibility, exhibits antimicrobial activity, supports the healing of wounds, etc. Electrospinning yields nanofibers which have wide applications, such as high-performance filters, biomaterial scaffolds for vascular grafts or wound dressings, etc. In this investigation, electrospinning was performed in an electric field of 0.6 kV/cm with a polyethylene oxide to chitosan ratio of 60:40. The polymer nanofibers had diameters that ranged from a few nanometers to several micrometers (approximately 30 nm).

Key Words: chitosan • polyethylene oxide (PEO) • electrospinning

Textile Research Journal, Vol. 78, No. 3, 254-257 (2008)
DOI: 10.1177/0040517507089752
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